Cutler connected with Brandon Stokley for a 48-yard touchdown to open the game, then threw 41 yards to Brandon Marshall for a third-quarter score as the Broncos improved to 5-5 and gained a share of the AFC West lead.
"The offensive line did a great job," Cutler said after completing 16 of 21 passes for 200 yards. "I barely got touched."
Rookie Andre Hall also created another big play with a 62-yard touchdown run in the fourth quarter that secured victory after Tennessee (6-4) had pulled the score to 27-20.
Vince Young sparked the Titans, throwing for one touchdown as he topped 300 yards passing and ran in another himself.
Denver went ahead 14-0 in the first quarter on Stokley's touchdown and Martinez's punt return before Young connected with Brandon Jones on a 21-yard touchdown pass in the second quarter.
Marshall pushed it out to 27-10 before Young then ran in his own touchdown from four yards in the third quarter, while Rob Bironas kicked a 37-yard field goal early in the fourth quarter to bring the deficit within a touchdown.
Hall, however, put the game beyond doubt with his long run.
Young completed 26 of 41 passes for 305 yards, but gave up two interceptions. He also rushed for 74 yards on 11 carries.
(Writing by Gene Cherry in Salvo, North Carolina; Editing by Greg Stutchbury)

